PRF (Platelet-Rich Fibrin) Benefits and Method of Preparati

PRF (Platelet-Rich Fibrin) Benefits and Method of Preparati

A PRF, or platelet-rich fibrin, injection is an advanced skin rejuvenation that restores the skin’s youthful appearance. It is an entirely natural alternative to dermal fillers because it harnesses the body’s built-in healing processes. But where does PRF come from, and how do medical professionals prepare it?

Keep reading to find out how a PRF injection works.

What is PRF?

Platelet-rich fibrin (PRF) is a type of fibrin that has many platelets in it. PRF is a second-generation form of platelet-rich plasma (PRP). Compared to PRP, PRF releases growth factors more gradually and is measured in days instead of hours.

PRF VS. PRP – Are There Differences?

Despite having the same regenerative applications, platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) have several key distinctions. A PRF tube contains no additives. A fibrin matrix forms because PRF is spun more slowly than PRP.

PRF is more focused on the growth factors that affect white blood cells. Unlike PRP, PRF growth factors take longer to release after injection.

How Useful is PRF?

PRF gives doctors a lot of alternatives because it can be applied as a membrane, a liquid, or an injection.

The following are treatments the effects of which PRF can boost:

  • Hair rejuvenation
  • Gaunt cheeks
  • Dental implants
  • Athletic injuries
  • Skin resurfacing
  • Dark circles beneath the eyes

How is PRF Prepared?

The PRF setup procedure is pretty straightforward. Without using anticoagulants, approximately 5 ml of blood is taken and put into a 6 ml vacutainer tube. After that, the vacutainer tubes are spun at 3000 revolutions per minute (rpm) for 10 minutes in a centrifugal machine.

PRP prepares the blood using anticoagulants and at high speed to destroy all red blood cells. On the other hand, PRF is prepared by spinning the tubes slower than PRP to isolate the platelets and white blood cells from the red blood cells. This procedure preserves the fibrin matrix without anticoagulants and permits a higher platelet concentration.

The blood will eventually separate into the following layers: a middle fraction containing a fibrin clot, a straw-colored upper layer of cellular plasma, and a lower layer of red blood cells.

The fibrin clot is then harvested at the center of the tube, right in the middle of the acellular plasma at the top and the red corpuscles at the bottom. The fibrin meshes contain a significant amount of platelets.

The fibrin matrix, where the PRF is, binds the platelets together and enables their release over 7 to 10 days. Longer-lasting effects occur from a slower release.

The Benefits of PRF

PRF boasts several benefits. Here are some of the most notable ones.

Reduced Wrinkles and Facial Folds

PRF guarantees and delivers a more youthful-looking complexion with fewer wrinkles. The effects of PRF include tightened skin, increased collagen production, and enhanced overall skin quality.

However, you won’t notice these effects as soon as the treatment is over. PRF takes time to affect the skin; you’ll see the first indications that your PRF treatment is working within 48 hours of getting the treatment.

Improved Under-Eye Loose Skin and Dark Circles

Since the skin beneath your eyes is the thinnest on your body, fine lines and wrinkles are sure to appear there more frequently. By removing wrinkles and filling in hollows, PRF can cure the signs of aging under-eye skin.

Dermal fillers used to be the standard aesthetic procedure for this delicate region of our faces. While fillers will rapidly fill in the hollows under the eyes, they may cause bloated or blue skin if utilized excessively. Additionally, fillers rarely work to reduce dark circles.

If you choose to get fillers with PRF, you can enhance the fillers’ effects while combating dark circles.

Repaired Skin Damage

Several issues can harm our skin cells, including dehydration, pollution, smoking, insufficient blood flow, and improper skin care practices. All of these factors and many more can contribute to the dreaded dull skin tone that ages our complexion by many years. 

PRF can moisturize your skin and increase blood flow to counteract the appearance of a tired complexion and even out skin tone by utilizing the healing properties of platelets. Additionally, PRF face injections are a successful acne scar treatment.

The platelet-rich fibrin therapy encourages the skin to manufacture more elastin for a younger appearance and smoother skin, making it a powerful ally against UV damage and the consequences of smoking.

Long Lasting Results

One benefit of the PRF operation is that it gives patients up to a year to enjoy the benefits. Only 2 to 5 appointments are required for the entire treatment, and the process only takes approximately 45 minutes. You will enjoy enhanced skin quality and texture, greater volume, and fewer dark circles for many months after the procedure.

But it’s essential to remember that every patient is unique, and everyone is affected by the treatment differently. The body’s growth factors and your blood are used to encourage skin regeneration. As a result, each person’s results will differ, and you could need your subsequent treatment sooner or later than you anticipated.

Conveniently Safe

There are no significant adverse effects from the PRF treatment, especially when carried out by qualified experts, so you don’t need to worry! The method employs the patient’s platelets and natural fibrin, which minimizes side effects, unlike synthetic fillers. The only possible adverse effects are slight bruising, swelling, discomfort, and mild pain.

Topical anesthetics and an ice pack can quickly alleviate these side effects. If you’re thinking about getting a PRF facial, we advise talking to your cosmetic doctor about your options. Even though there aren’t many contraindications to the surgery, patients with low or abnormal platelets or patients taking anti-clotting drugs should choose a different facial therapy.

Kora Aesthetics Prepares the Best PRF Treatments

The efficacy of PRF is all in the preparation. Kora Aesthetics provides the best PRF treatment in Arizona.

Contact Kora Aesthetics immediately to learn more about the PRF process or to make an appointment. Kora Aesthetics is the best cosmetic clinic for natural beauty. Contact us by phone at (480) 630-7566, by email at, or by using the form below. Our office is at 7077 East. Scottsdale, Arizona 85254, 200 and 404 Bell Road, Suites.

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